Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645588 | 0.89 | MAPT (0.43) | MAPTTHRBRXFP1SMN1; SMN2P2RX7 | |
| SCHEMBL29646039 | 0.89 | C1R (0.40) | MAPTTHRBRXFP1SMN1; SMN2TP53 | |
| SCHEMBL29645518 | 0.88 | C1R (0.38) | MAPTTHRBSMN1; SMN2TP53LMNA | |
| SCHEMBL29645715 | 0.88 | MAPT (0.39) | MAPTTHRBTP53LMNAC1R | |
| SCHEMBL29645580 | 0.88 | P2RX7 (0.36) | MAPTTHRBRXFP1SMN1; SMN2P2RX7 | |
| SCHEMBL29645893 | 0.88 | MAPT (0.45) | MAPTTHRBRXFP1SMN1; SMN2TP53 | |
| SCHEMBL29645459 | 0.88 | C1R (0.43) | MAPTTHRBRXFP1SMN1; SMN2TP53 | |
| SCHEMBL29645672 | 0.87 | MAPT (0.46) | MAPTTHRBRXFP1SMN1; SMN2P2RX7 | |
| SCHEMBL29645596 | 0.85 | C1R (0.39) | MAPTTHRBRXFP1SMN1; SMN2TP53 | |
| SCHEMBL29646060 | 0.84 | TP53 (0.47) | MAPTTHRBRXFP1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |