SCHEMBL2964564

SCHEMBL2964564

CC(=O)Nc1ccc2c(c1)Cc1cccc(NC(C)=O)c1-2

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.68
CYP1A2 P05177 2/20 0.68
ADRA2A P08913 1/20 0.68
SLC6A2 P23975 1/20 0.68
HTR2C P28335 1/20 0.68
SLC6A4 P31645 1/20 0.68
HTR2B P41595 1/20 0.68
RAB9A P51151 6/20 0.56
NPC1 O15118 4/20 0.56
HSP90AA1 P07900 1/20 0.51
TLR9 Q9NR96 1/20 0.51
BAZ2B Q9UIF8 1/20 0.48
KMT2A Q03164 2/20 0.48
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HSD17B10 Q99714 1/20 0.46
MAPK1 P28482 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11657836 0.85 CYP1A2 (0.51) MAOACYP1A2ADRA2ASLC6A2HTR2C
SCHEMBL1273609 0.84 NPC1 (0.68) MAOACYP1A2ADRA2ASLC6A2HTR2C
SCHEMBL30002207 0.84 NPC1 (0.68) MAOACYP1A2ADRA2ASLC6A2HTR2C
SCHEMBL2962505 0.82 MAOA (0.84) MAOACYP1A2ADRA2ASLC6A2HTR2C
2-Acetylaminofluorene SCHEMBL21114365 0.81 CYP1A2 (1.00) MAOACYP1A2ADRA2ASLC6A2HTR2C
2-Acetylaminofluorene SCHEMBL29364009 0.81 CYP1A2 (1.00) MAOACYP1A2ADRA2ASLC6A2HTR2C
2-Acetylaminofluorene SCHEMBL75140 0.81 CYP1A2 (1.00) MAOACYP1A2ADRA2ASLC6A2HTR2C
2-Acetylaminofluorene SCHEMBL29829339 0.81 CYP1A2 (1.00) MAOACYP1A2ADRA2ASLC6A2HTR2C
SCHEMBL31420066 0.80 KMT2A (0.51) MAOACYP1A2ADRA2ASLC6A2HTR2C
2-Acetylaminofluorene SCHEMBL6903872 0.80 CYP1A2 (0.97) MAOACYP1A2ADRA2ASLC6A2HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7772009-B2 Room temperature phosphorescence apparatus and methods SCR Research, LLC (US) 2010-08-10 US claimed
WO-2007061574-A2 ROOM TEMPERATURE PHOSPHORESCENCE APPARATUS AND METHODS SCA RESEARCH, LLC (US) 2007-05-31 WO claimed
US-20070117215-A1 Room temperature phosphorescence apparatus and methods POLYMER CONCEPTS TECHNOLOGIES PBY, INC. 2007-05-24 US claimed
US-7772009-B2 Room temperature phosphorescence apparatus and methods SCR Research, LLC (US) 2010-08-10 US disclosed
WO-2007061574-A2 ROOM TEMPERATURE PHOSPHORESCENCE APPARATUS AND METHODS SCA RESEARCH, LLC (US) 2007-05-31 WO disclosed
US-20070117215-A1 Room temperature phosphorescence apparatus and methods POLYMER CONCEPTS TECHNOLOGIES PBY, INC. 2007-05-24 US disclosed