Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273609 | 1.00 | NPC1 (0.68) | NPC1RAB9AMAOACYP1A2HTR2B | |
| SCHEMBL9279689 | 0.89 | MAOA (0.66) | NPC1RAB9AMAOACYP1A2HTR2B | |
| SCHEMBL2964564 | 0.84 | MAOA (0.68) | NPC1RAB9AMAOACYP1A2HTR2B | |
| SCHEMBL144325 | 0.81 | NPC1 (1.00) | NPC1RAB9AMAOACYP1A2HTR2B | |
| SCHEMBL15671596 | 0.79 | TERT (0.45) | NPC1RAB9AHTR2BALDH1A1HPGD | |
| SCHEMBL11740054 | 0.77 | NPC1 (0.81) | NPC1RAB9AMAOACYP1A2HTR2B | |
| SCHEMBL2526502 | 0.77 | MAOA (0.45) | NPC1RAB9AMAOACYP1A2HTR2B | |
| Sulfuric Acid SCHEMBL28964142 | 0.76 | NPC1 (0.89) | NPC1RAB9AMAOACYP1A2HTR2B | |
| SCHEMBL16865877 | 0.75 | MAOA (0.59) | NPC1RAB9AMAOACYP1A2ALDH1A1 | |
| SCHEMBL15580935 | 0.75 | MAOA (0.59) | NPC1RAB9AMAOACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220748-A1 | SYNTHESIS OF POLYNUCLEOTIDE BOTTLEBRUSH POLYMER | ILLUMINA SINGAPORE PTE. LTD. (SG) | 2022-10-20 | — | — | WO | disclosed |