Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | TTK | P33981 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | LITAF | Q99732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645614 | 0.89 | TTK (0.39) | TP53ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL29646030 | 0.89 | KMT2A (0.35) | TP53ADORA2AADORA1ADORA3MAPT | |
| SCHEMBL29646043 | 0.86 | BRD4 (0.39) | TP53ADORA2AADORA1KCNH2MAPT | |
| SCHEMBL29645615 | 0.85 | ADORA3 (0.40) | TP53ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL29645523 | 0.84 | BRD4 (0.36) | TP53ADORA2ATTKTNFLITAF | |
| SCHEMBL29645741 | 0.84 | KDM4E (0.48) | TP53ADORA2AADORA1ADORA3MAPT | |
| SCHEMBL29645807 | 0.83 | TP53 (0.39) | TP53MAPTPOLBTHRBSMN1; SMN2 | |
| SCHEMBL29646140 | 0.81 | POLB (0.45) | TP53ADORA2AADORA1ADORA3MAPT | |
| SCHEMBL31150088 | 0.81 | JAK2 (0.34) | TP53ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL31150111 | 0.81 | JAK2 (0.34) | TP53ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |