Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | STK10 | O94804 | 1/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645837 | 0.87 | EGFR (0.36) | TP53ALDH1A1KDM4ESMN1; SMN2CDK2 | |
| SCHEMBL29645741 | 0.87 | KDM4E (0.48) | TP53ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL29645614 | 0.85 | TTK (0.39) | TP53ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL29645654 | 0.85 | MAPT (0.43) | TP53MAPTTHRBSMN1; SMN2POLB | |
| SCHEMBL29645641 | 0.83 | TP53 (0.39) | TP53KDM4EMAPTTHRBSMN1; SMN2 | |
| SCHEMBL29646043 | 0.82 | BRD4 (0.39) | TP53MAPTTHRBSMN1; SMN2TTK | |
| SCHEMBL29646116 | 0.81 | ADORA2A (0.38) | TP53MAPTTHRBSMN1; SMN2P2RX7 | |
| SCHEMBL29645523 | 0.81 | BRD4 (0.36) | TP53TTK | |
| SCHEMBL29646140 | 0.80 | POLB (0.45) | TP53ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL31149938 | 0.79 | KDM4E (0.43) | TP53ALDH1A1KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |