Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31150004 | 0.92 | ADORA3 (0.31) | KDM4EALDH1A1HPGDADORA3ADORA2A | |
| SCHEMBL29646056 | 0.88 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDADORA3ADORA2A | |
| SCHEMBL29646105 | 0.88 | ADORA2A (0.38) | KDM4EALDH1A1HPGDADORA3ADORA2A | |
| SCHEMBL29646061 | 0.87 | KDM4E (0.34) | KDM4EALDH1A1HPGDADORA3ADORA2A | |
| SCHEMBL29645592 | 0.86 | CYP1A2 (0.35) | KDM4EALDH1A1HPGDADORA3ADORA2A | |
| SCHEMBL29645615 | 0.86 | ADORA3 (0.40) | ADORA3ADORA2AADORA1ADORA2BP2RX7 | |
| SCHEMBL31150093 | 0.79 | ADORA2A (0.37) | ADORA3ADORA2AADORA1ADORA2BP2RX7 | |
| SCHEMBL31150095 | 0.79 | ADORA3 (0.33) | KDM4EALDH1A1HPGDADORA3ADORA2A | |
| SCHEMBL29646037 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1ADORA3ADORA2AADORA1 | |
| SCHEMBL29645692 | 0.78 | BRD4 (0.32) | PABPC1EIF4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |