Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31150047 | 0.91 | CYP1A2 (0.35) | CYP1A2LRRK2P2RX7ADORA3ADORA2A | |
| SCHEMBL29646056 | 0.89 | ALDH1A1 (0.34) | P2RX7ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL29646105 | 0.89 | ADORA2A (0.38) | P2RX7ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL29646061 | 0.88 | KDM4E (0.34) | P2RX7ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL29646221 | 0.88 | CYP1A2 (0.35) | CYP1A2LRRK2P2RX7MAPT | |
| SCHEMBL29645615 | 0.87 | ADORA3 (0.40) | P2RX7ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL29645798 | 0.86 | KDM4E (0.33) | P2RX7ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL29646123 | 0.85 | P2RX7 (0.33) | P2RX7KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL29645597 | 0.83 | TRPA1 (0.34) | LRRK2P2RX7 | |
| SCHEMBL29646083 | 0.82 | MAPT (0.35) | P2RX7MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |