Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645807 | 0.87 | TP53 (0.39) | SLC40A1P2RX7CDK2ROCK2ROCK1 | |
| SCHEMBL29645682 | 0.86 | ADORA3 (0.40) | P2RX7XDHTP53SMN1; SMN2RXFP1 | |
| SCHEMBL29645803 | 0.85 | POLB (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29645914 | 0.85 | NR1H2 (0.40) | P2RX7XDH | |
| SCHEMBL29645600 | 0.85 | PDK2 (0.32) | SLC40A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29646148 | 0.84 | LMNA (0.39) | CSNK1DTP53RXFP1 | |
| SCHEMBL29645878 | 0.84 | HSP90AA1 (0.35) | SLC40A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29645654 | 0.84 | MAPT (0.43) | POLBTP53SMN1; SMN2RXFP1 | |
| SCHEMBL29645745 | 0.84 | PSEN1 (0.34) | SLC40A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29645738 | 0.82 | NTRK1 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |