Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645702 | 0.91 | MAPT (0.41) | MAPTADKPOLBTP53KMT2A | |
| SCHEMBL29645527 | 0.88 | MAPT (0.41) | MAPTADKPOLBTP53 | |
| SCHEMBL29646169 | 0.86 | MAPT (0.37) | MAPTADKHCRTR1POLBTP53 | |
| SCHEMBL29645893 | 0.86 | MAPT (0.45) | MAPTPOLBTP53KDM4EALDH1A1 | |
| SCHEMBL29645674 | 0.85 | MAPT (0.41) | MAPTADKPOLBTP53KMT2A | |
| SCHEMBL29645638 | 0.85 | MAPT (0.40) | MAPTADKPOLBTP53KMT2A | |
| SCHEMBL29645843 | 0.84 | KMT2A (0.44) | MAPTADKHCRTR1POLBTP53 | |
| SCHEMBL29645834 | 0.84 | ADORA3 (0.49) | MAPTHCRTR1POLBTP53KDM4E | |
| SCHEMBL29645571 | 0.84 | MAPT (0.46) | MAPTHCRTR1POLBTP53KDM4E | |
| SCHEMBL29645608 | 0.84 | MAPT (0.40) | MAPTADKPOLBTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |