Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645672 | 0.90 | MAPT (0.46) | MAPTTHRBRXFP1SMN1; SMN2POLB | |
| SCHEMBL29645765 | 0.90 | MAPT (0.39) | MAPTTHRBRXFP1SMN1; SMN2ADORA3 | |
| SCHEMBL29645588 | 0.89 | MAPT (0.43) | MAPTTHRBRXFP1SMN1; SMN2POLB | |
| SCHEMBL29645642 | 0.88 | MAPT (0.43) | MAPTTHRBRXFP1SMN1; SMN2POLB | |
| SCHEMBL29645702 | 0.88 | MAPT (0.41) | MAPTRXFP1POLBADORA3TP53 | |
| SCHEMBL29645868 | 0.86 | MAPT (0.37) | MAPTRXFP1SMN1; SMN2POLBADORA3 | |
| SCHEMBL29645527 | 0.86 | MAPT (0.41) | MAPTPOLBTP53 | |
| SCHEMBL29646169 | 0.86 | MAPT (0.37) | MAPTTHRBRXFP1SMN1; SMN2POLB | |
| SCHEMBL29645487 | 0.85 | MAPT (0.59) | MAPTTHRBRXFP1SMN1; SMN2POLB | |
| SCHEMBL29646060 | 0.85 | TP53 (0.47) | MAPTTHRBRXFP1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |