Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31149876 | 0.92 | P2RX7 (0.35) | P2RX7SCN9ASCN5ATTK | |
| SCHEMBL29645723 | 0.91 | P2RX7 (0.36) | P2RX7TNKS | |
| SCHEMBL29645564 | 0.89 | P2RX7 (0.37) | P2RX7SCN9ATNKS | |
| SCHEMBL29645931 | 0.86 | MAPT (0.39) | P2RX7 | |
| SCHEMBL29645914 | 0.84 | NR1H2 (0.40) | P2RX7 | |
| SCHEMBL31150091 | 0.83 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL29645960 | 0.81 | P2RX7 (0.33) | P2RX7TNKS | |
| SCHEMBL22987643 | 0.81 | HSD11B1 (0.35) | SCN9A | |
| SCHEMBL29646221 | 0.79 | CYP1A2 (0.35) | P2RX7 | |
| SCHEMBL29645715 | 0.79 | MAPT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |