Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645577 | 0.95 | MAPT (0.45) | MAPTTHRBTP53KDM4EPOLB | |
| SCHEMBL29645889 | 0.93 | MAPT (0.47) | MAPTTHRBTP53KDM4EPOLB | |
| SCHEMBL29645943 | 0.93 | MAPT (0.50) | MAPTTHRBTP53KDM4EPOLB | |
| SCHEMBL29645764 | 0.92 | ADORA3 (0.43) | MAPTTP53POLBADORA3RXFP1 | |
| SCHEMBL29646058 | 0.91 | MAPT (0.47) | MAPTTHRBTP53KDM4EPOLB | |
| SCHEMBL29645491 | 0.90 | MAPT (0.48) | MAPTTHRBTP53KDM4EPOLB | |
| SCHEMBL29646002 | 0.90 | MAPT (0.48) | MAPTTHRBTP53KDM4EPOLB | |
| SCHEMBL31150079 | 0.90 | THRB (0.44) | MAPTTHRBTP53KDM4EPOLB | |
| SCHEMBL29645698 | 0.90 | ADORA3 (0.54) | MAPTTHRBTP53KDM4EPOLB | |
| SCHEMBL29645487 | 0.89 | MAPT (0.59) | MAPTTHRBTP53KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |