Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645503 | 0.92 | ADORA3 (0.49) | ADORA3ADORA1MAPTADORA2ATP53 | |
| SCHEMBL29645988 | 0.92 | MAPT (0.47) | ADORA3ADORA1MAPTADORA2ATP53 | |
| SCHEMBL29645909 | 0.91 | ADORA3 (0.44) | ADORA3ADORA1MAPTADORA2ATP53 | |
| SCHEMBL29645577 | 0.90 | MAPT (0.45) | ADORA3ADORA1MAPTTP53POLB | |
| SCHEMBL29645913 | 0.88 | CCNC (0.39) | MAPT | |
| SCHEMBL29645874 | 0.87 | ADORA3 (0.40) | ADORA3ADORA1MAPTADORA2A | |
| SCHEMBL29646058 | 0.86 | MAPT (0.47) | MAPTTP53POLBRXFP1 | |
| SCHEMBL29645458 | 0.85 | MAPT (0.50) | ADORA3ADORA1MAPTTP53POLB | |
| SCHEMBL29645760 | 0.84 | MAPT (0.56) | ADORA3ADORA1MAPTTP53POLB | |
| SCHEMBL29645731 | 0.84 | MAPT (0.44) | ADORA3ADORA1MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |