Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979556 | 1.00 | ADORA3 (0.40) | ADORA3ADORA1PDE10ATP53MAPT | |
| SCHEMBL25118631 | 0.85 | CYP1A2 (0.49) | ADORA3ADORA1TP53MAPTTHRB | |
| SCHEMBL29646374 | 0.85 | CYP1A2 (0.49) | ADORA3ADORA1TP53MAPTTHRB | |
| SCHEMBL22987662 | 0.84 | ADORA3 (0.46) | ADORA3ADORA1PDE10AMAPTPOLB | |
| SCHEMBL30393859 | 0.78 | NPC1 (0.57) | PDE10ATP53MAPTTHRBPOLB | |
| SCHEMBL29646428 | 0.76 | ADORA3 (0.50) | ADORA3ADORA1PDE10AMAPTSMN1; SMN2 | |
| SCHEMBL22979102 | 0.76 | ADORA3 (0.50) | ADORA3ADORA1PDE10AMAPTSMN1; SMN2 | |
| SCHEMBL22987398 | 0.76 | HPGD (0.51) | ADORA3ADORA1TP53MAPTTHRB | |
| SCHEMBL29646409 | 0.76 | HPGD (0.51) | ADORA3ADORA1TP53MAPTTHRB | |
| SCHEMBL22979306 | 0.76 | ADORA3 (0.65) | ADORA3ADORA1MAPTTHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |