Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | USP2 | O75604 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25118631 | 1.00 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2D6TSHRHSD17B10 | |
| SCHEMBL22987934 | 0.86 | ADORA3 (0.51) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22979556 | 0.85 | ADORA3 (0.40) | HSD17B10LMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL29646313 | 0.85 | ADORA3 (0.40) | HSD17B10LMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL29646400 | 0.85 | C1R (0.42) | ADORA3ADORA1MAPTC1R | |
| SCHEMBL22987859 | 0.85 | ADORA3 (0.42) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL22979544 | 0.85 | C1R (0.42) | ADORA3ADORA1MAPTC1R | |
| SCHEMBL22980067 | 0.83 | TP53 (0.47) | MAPK1TP53ADORA2APOLBADORA3 | |
| SCHEMBL22979102 | 0.83 | ADORA3 (0.50) | CYP1A2CYP3A4CYP2D6TSHRHSD17B10 | |
| SCHEMBL29646419 | 0.83 | TP53 (0.47) | MAPK1TP53ADORA2APOLBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |