Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4886622 | 0.77 | CHRNA7 (0.40) | ALDH1A1EGFRTDP1CHRNA7CHRNA10 | |
| Hydrochloric Acid SCHEMBL4886619 | 0.77 | CHRNA7 (0.40) | ALDH1A1EGFRTDP1CHRNA7CHRNA10 | |
| Hydrochloric Acid SCHEMBL8070163 | 0.74 | CHRNA7 (0.47) | EGFRTDP1CHRNA7CHRNA10CHRNA9 | |
| Hydrochloric Acid SCHEMBL8660307 | 0.74 | CHRNA7 (0.47) | EGFRTDP1CHRNA7CHRNA10CHRNA9 | |
| Hydrochloric Acid SCHEMBL9615591 | 0.71 | CHRNA7 (0.43) | ALDH1A1EGFRCHRNA7CHRNA10CHRNA9 | |
| Hydrochloric Acid SCHEMBL32674559 | 0.68 | KMT2A (0.55) | ALDH1A1EGFRTDP1CHRNA7CHRNA10 | |
| Hydrochloric Acid SCHEMBL7145938 | 0.68 | SMN1; SMN2 (0.47) | ALDH1A1EGFRTDP1CHRNA7CHRNA10 | |
| Hydrochloric Acid SCHEMBL8070951 | 0.68 | KMT2A (0.55) | ALDH1A1EGFRTDP1CHRNA7CHRNA10 | |
| Hydrochloric Acid SCHEMBL7145936 | 0.68 | SMN1; SMN2 (0.47) | ALDH1A1EGFRTDP1CHRNA7CHRNA10 | |
| SCHEMBL11081808 | 0.66 | DNM1 (0.54) | ALDH1A1EGFRTDP1CHRNA7CHRNA10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255994-A1 | CLEAR COATING ANTIMICROBIAL COMPOSITIONS, METHODS OF PREPARATION, AND USES THEREOF FOR CONFERRING ANTIMICROBIAL ACTIVITY TO A SURFACE | Polyamyna Nanotech Inc. (CA) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022118177-A1 | CLEAR COATING ANTIMICROBIAL COMPOSITIONS, METHODS OF PREPARATION, AND USES THEREOF FOR CONFERRING ANTIMICROBIAL ACTIVITY TO A SURFACE | POLYAMYNA NANOTECH INC. (CA) | 2022-06-09 | — | — | WO | disclosed |