SCHEMBL296473

SCHEMBL296473

OCCc1ccc2ccccc2n1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 5/20 0.50
CYSLTR1 Q9Y271 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYSLTR2 Q9NS75 1/20 0.50
GPBAR1 Q8TDU6 3/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL898777 0.88 PDE10A (0.47) PDE10ACYSLTR1CYP1A2CYSLTR2GPBAR1
SCHEMBL2913941 0.87 PDE10A (0.61) PDE10ACYSLTR1CYP1A2CYSLTR2CYP3A4
SCHEMBL9598037 0.86 CYSLTR1 (0.46) PDE10ACYSLTR1CYP1A2CYSLTR2GPBAR1
Hydrochloric Acid SCHEMBL29127709 0.86 PDE10A (0.46) PDE10ACYSLTR1CYP1A2CYSLTR2GPBAR1
SCHEMBL1783030 0.85 CYSLTR1 (0.45) PDE10ACYSLTR1CYP1A2CYSLTR2GPBAR1
SCHEMBL11028869 0.85 CYSLTR1 (0.45) PDE10ACYSLTR1CYP1A2CYSLTR2GPBAR1
SCHEMBL12603960 0.85 CYSLTR1 (0.45) PDE10ACYSLTR1CYP1A2CYSLTR2GPBAR1
SCHEMBL12603937 0.85 CYSLTR1 (0.45) PDE10ACYSLTR1CYP1A2CYSLTR2GPBAR1
SCHEMBL9186483 0.85 CYSLTR1 (0.45) PDE10ACYSLTR1CYP1A2CYSLTR2GPBAR1
SCHEMBL1551574 0.85 CYSLTR1 (0.45) PDE10ACYSLTR1CYP1A2CYSLTR2GPBAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 WO claimed
EP-2390250-B1 GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS, MANUFACTURING METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME SK CHEMICALS CO LTD (KR) 2015-08-12 EP claimed
US-9034850-B2 Gonadotropin releasing hormone receptor antagonist, preparation method thereof and pharmaceutical composition comprising the same SK CHEMICALS CO., LTD. (KR) 2015-05-19 US claimed
EP-2337124-B1 Electrochemical gas development cell, in particular mercury-free hydrogen development cell SIMATEC AG (CH) 2014-05-07 EP claimed
US-20130137661-A1 Gonadotropin Releasing Hormone Receptor Antagonist, Preparation Method Thereof And Pharmaceutical Composition Comprising The Same SK CHEMICALS CO. LTD. (KR) 2013-05-30 US claimed
EP-2034998-A1 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS Janssen Pharmaceutica, N.V. (BE) 2009-03-18 EP claimed
WO-2008079427-A1 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2008-07-03 WO claimed
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 WO disclosed
WO-2024081635-A2 TARGETED QUINOCYANINE DYES FOR THE INTRAOPERATIVE DELINEATION OF CANCER MARGINS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-04-18 WO disclosed
EP-4219477-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2023-08-02 EP disclosed
CN-116410132-A 8-hydroxyquinoline compound, preparation method thereof and application thereof in preparation of antitumor drugs 广东工业大学 2023-07-11 CN disclosed
US-11688845-B2 Method for passive metal activation and uses thereof TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2023-06-27 US disclosed
EP-3908269-A1 COMBINATION IN THE TREATMENT OF NONTUBERCULOUS MYCOBACTERIAL DISEASES Janssen Pharmaceutica NV (BE) 2021-11-17 EP disclosed
US-4634767-A Method for preparing spiro(indoline)-type photochromic compounds PPG INDUSTRIES, INC. (US) 1987-01-06 US disclosed
US-4433017-A IONIZABLE GROUP DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1984-02-21 US disclosed
US-4242516-A Fluorinated amphoteric surfactants CIBA-GEIGY CORPORATION (US) 1980-12-30 US disclosed
US-4161602-A Fluorinated amphoteric and cationic surfactants containing a pyridinium moiety CIBA-GEIGY CORPORATION (US) 1979-07-17 US disclosed
US-4161590-A Fluorinated amphoteric and cationic surfactants CIBA-GEIGY CORPORATION (US) 1979-07-17 US disclosed
US-4069244-A THIO-CARBOXYLIC ACIDS CIBA-GEIGY CORPORATION (US) 1978-01-17 US disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130137661-A1 Gonadotropin Releasing Hormone Receptor Antagonist, Preparation Method Thereof And Pharmaceutical Composition Comprising The Same GNRHR, GHRHR, LHCGR PDE10A 610/4885CYSLTR1 1148/4885CYP1A2 1435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.