Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 8/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14861582 | 1.00 | LMNA (0.48) | LMNAMAPTHPGDTRPA1ABCG2 | |
| SCHEMBL3413002 | 0.87 | ABCG2 (0.54) | LMNAMAPTHPGDABCG2 | |
| SCHEMBL3408510 | 0.86 | ABCG2 (0.56) | LMNAHPGDABCG2GRM4 | |
| SCHEMBL3602136 | 0.85 | ABCG2 (0.47) | LMNAMAPTHPGDABCG2 | |
| SCHEMBL3409105 | 0.84 | ABCG2 (0.52) | MAPTHPGDTRPA1ABCG2 | |
| SCHEMBL16492396 | 0.84 | ABCG2 (0.55) | MAPTABCG2 | |
| SCHEMBL14861915 | 0.82 | ABCG2 (0.56) | ABCG2 | |
| SCHEMBL3600310 | 0.82 | ABCG2 (0.52) | LMNAMAPTABCG2 | |
| SCHEMBL3415833 | 0.82 | MAPT (0.52) | LMNAMAPTABCG2 | |
| SCHEMBL3592180 | 0.81 | MAPT (0.55) | LMNAMAPTHPGDABCG2GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766367-B1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for the treatment of viral infections, in particular picornavirus infections | SCANDION ONCOLOGY AS (DK) | 2022-05-18 | — | — | EP | disclosed |