Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 15/20 | 1.00 |
| ▸ | GSK3B | P49841 | 15/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 14/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 14/20 | 1.00 |
| ▸ | FLT3 | P36888 | 6/20 | 1.00 |
| ▸ | CDK2 | P24941 | 3/20 | 0.74 |
| ▸ | STK17B | O94768 | 2/20 | 0.74 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.74 |
| ▸ | CDK1 | P06493 | 7/20 | 0.73 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.73 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.73 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.73 |
| ▸ | CDK4 | P11802 | 2/20 | 0.73 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.73 |
| ▸ | CCND1 | P24385 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | CDK14 | O94921 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | SRC | P12931 | 1/20 | 0.73 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273058 | 0.85 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1FLT3 | |
| SCHEMBL29961097 | 0.85 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1FLT3 | |
| SCHEMBL29421607 | 0.84 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1FLT3 | |
| SCHEMBL30597665 | 0.82 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1FLT3 | |
| SCHEMBL30597679 | 0.78 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1FLT3 | |
| SCHEMBL30319807 | 0.78 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1FLT3 | |
| SCHEMBL30094663 | 0.78 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1FLT3 | |
| SCHEMBL30597674 | 0.78 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1FLT3 | |
| SCHEMBL30380971 | 0.77 | GSK3A (0.70) | GSK3AGSK3BCDK5CDK5R1FLT3 | |
| SCHEMBL30597663 | 0.75 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4687928-A1 | GENERATION OF BRANCHING URETERIC BUD AND COLLECTING DUCT ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | The Brigham & Women's Hospital, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4473093-A1 | GENERATION OF BROWN ADIPOCYTES FROM HUMAN PLURIPOTENT STEM CELLS | The Brigham and Women's Hospital, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2024233940-A1 | CELL REPLACEMENT THERAPY FOR PULMONARY DISEASES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024206297-A1 | GENERATION OF BRANCHING URETERIC BUD AND COLLECTING DUCT ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2024-10-03 | — | — | WO | disclosed |
| EP-3866786-B1 | COMPOSITIONS AND METHODS FOR SUPPRESSING AND/OR TREATING METABOLIC DISEASES AND/OR A CLINICAL CONDITION THEREOF | CK REGEON INC (KR) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023150555-A1 | GENERATION OF BROWN ADIPOCYTES FROM HUMAN PLURIPOTENT STEM CELLS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| CN-115969814-A | Novel pharmaceutical formulations containing indirubin and derivatives thereof and methods of making and using the same | 法斯瑞斯公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-112920191-B | Arylethynyl oxindole oxirane as well as preparation method and application thereof | 南宁师范大学 | 2022-03-25 | — | — | CN | disclosed |