Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 15/20 | 0.70 |
| ▸ | GSK3B | P49841 | 15/20 | 0.70 |
| ▸ | CDK5 | Q00535 | 14/20 | 0.70 |
| ▸ | CDK5R1 | Q15078 | 14/20 | 0.70 |
| ▸ | CDK1 | P06493 | 9/20 | 0.70 |
| ▸ | CCNB2 | O95067 | 8/20 | 0.70 |
| ▸ | CCNB1 | P14635 | 8/20 | 0.70 |
| ▸ | CCNB3 | Q8WWL7 | 8/20 | 0.70 |
| ▸ | CDK2 | P24941 | 3/20 | 0.70 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.70 |
| ▸ | CDK4 | P11802 | 2/20 | 0.70 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.70 |
| ▸ | CCND1 | P24385 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | CDK14 | O94921 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | SRC | P12931 | 1/20 | 0.70 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.70 |
| ▸ | CDK11B | P21127 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421607 | 0.83 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30319807 | 0.77 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL29648491 | 0.77 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30094663 | 0.77 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30597674 | 0.77 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30273058 | 0.77 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30597679 | 0.77 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30319805 | 0.73 | GSK3A (0.76) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30319862 | 0.72 | GSK3A (0.74) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30319763 | 0.72 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12516022-B2 | Derivatives of aryl hydrocarbon receptor agonists | AZORA THERAPEUTICS, INC. (US) | 2026-01-06 | — | — | US | disclosed |
| EP-4412991-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AZORA THERAPEUTICS, INC. (US) | 2024-08-14 | — | — | EP | disclosed |
| US-20240182416-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AZORA THERAPEUTICS, INC. | 2024-06-06 | — | — | US | disclosed |
| US-11834412-B2 | Derivatives of aryl hydrocarbon receptor agonists | AZORA THERAPEUTICS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230227408-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AZORA THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
| WO-2023060268-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AZORA THERAPEUTICS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227408-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AHR, ARNT, NR4A1 | GSK3A 1729/4885GSK3B 1639/4885CDK5 3486/4885 |
| US-11834412-B2 | Derivatives of aryl hydrocarbon receptor agonists | AHR, ARNT, NR4A1 | GSK3A 1729/4885GSK3B 1639/4885CDK5 3486/4885 |
| US-20240182416-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AHR, ARNT, NR4A1 | GSK3A 1729/4885GSK3B 1639/4885CDK5 3486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.