SCHEMBL29421607

SCHEMBL29421607

O=C1C(c2c(O)[nH]c3ccccc23)=Nc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 14/20 1.00
GSK3B P49841 14/20 1.00
CDK5 Q00535 11/20 1.00
CDK5R1 Q15078 10/20 1.00
CDK1 P06493 5/20 1.00
CCNB2 O95067 4/20 1.00
CCNB1 P14635 4/20 1.00
CCNB3 Q8WWL7 4/20 1.00
CDK2 P24941 4/20 1.00
CCNE1 P24864 3/20 1.00
SRC P12931 2/20 1.00
CTRB1 P17538 2/20 1.00
AHR P35869 2/20 1.00
CDK4 P11802 2/20 1.00
CCNA2 P20248 2/20 1.00
CCND1 P24385 2/20 1.00
MEN1 O00255 1/20 1.00
CDK14 O94921 1/20 1.00
MAPT P10636 1/20 1.00
CDK11B P21127 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30094663 0.84 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL30597679 0.84 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL29648491 0.84 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL30273058 0.84 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL29975793 0.84 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL30319807 0.84 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL30597674 0.84 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL30380971 0.83 GSK3A (0.70) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL23064865 0.82 CDK2 (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL29353719 0.82 CDK2 (1.00) GSK3AGSK3BCDK5CDK5R1CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3583644-B1 ELECTRODE MATERIALS AND PROCESSES FOR THEIR PREPARATION HYDRO QUEBEC (CA) 2024-08-07 EP claimed
CN-114540278-A Microvessel in-vitro culture method and culture solution 青岛大学 2022-05-27 CN claimed
EP-4633612-A1 FIXED DOSE COMBINATION COMPRISING NETUPITANT AND PALONOSETRON Alfred E. Tiefenbacher (GmbH & Co. KG) (DE) 2025-10-22 EP disclosed
EP-4633608-A1 ANTIOXIDANT-FREE FIXED DOSE COMBINATION OF NETUPITANT AND PALONOSETRON Alfred E. Tiefenbacher (GmbH & Co. KG) (DE) 2025-10-22 EP disclosed
CN-115851780-B Flavin monooxygenase gene ScFMO, protein coded by same and application thereof 中国人民解放军海军军医大学 2025-04-15 CN disclosed
US-20240252688-A1 COMPOSITIONS AND METHODS FOR ENHANCED PROTEIN PRODUCTION HDT BIO CORP. 2024-08-01 US disclosed
WO-2024126398-A1 FIXED DOSE COMBINATION COMPRISING NETUPITANT AND PALONOSETRON ALFRED E. TIEFENBACHER (GMBH & CO. KG) (DE) 2024-06-20 WO disclosed
WO-2024126408-A1 ANTIOXIDANT-FREE FIXED DOSE COMBINATION OF NETUPITANT AND PALONOSETRON ALFRED E. TIEFENBACHER (GMBH & CO. KG) (DE) 2024-06-20 WO disclosed
US-20240034799-A1 METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS CEDARS SINAI MEDICAL CENTER (US) 2024-02-01 US disclosed
EP-4256086-A1 METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS Cedars-Sinai Medical Center (US) 2023-10-11 EP disclosed
US-20230279491-A1 TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS CEDARS-SINAI MEDICAL CENTER 2023-09-07 US disclosed
US-11511028-B2 Extracorporeal drug removal for intravascular triggered drug delivery systems MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2022-11-29 US disclosed
CN-115397452-A Lung biomarkers and methods of use thereof 普罗科技有限公司 2022-11-25 CN disclosed
US-20220354845-A1 METHODS FOR ENHANCING DNA DAMAGE AND APOPTOSIS OF LEUKEMIC CELLS UNIV JEFFERSON (US) 2022-11-10 US disclosed
CN-114933585-A Therapeutically active compounds and methods of use thereof 法国施维雅药厂 2022-08-23 CN disclosed
CN-108026159-B9 BTLA fusion protein agonists and uses thereof 桑福德伯纳姆普利斯医学发现研究所 2022-07-05 CN disclosed
WO-2022119842-A1 METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS CEDARS-SINAI MEDICAL CENTER (US) 2022-06-09 WO disclosed
CN-108026159-B BTLA fusion protein agonists and uses thereof 桑福德伯纳姆普利斯医学发现研究所 2022-05-27 CN disclosed
US-11318138-B2 Methods for treating B cell proliferative disorders CORNELL UNIVERSITY (US) 2022-05-03 US disclosed
CN-114206392-A Immunomodulatory agent antibody drug conjugates and uses thereof 苏特罗生物制药公司 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11318138-B2 Methods for treating B cell proliferative disorders CDK4, BCL6, BCL6B GSK3A 308/4885GSK3B 198/4885CDK5 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.