Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 16/20 | 1.00 |
| ▸ | GSK3B | P49841 | 16/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 13/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 13/20 | 1.00 |
| ▸ | CDK1 | P06493 | 9/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 8/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 8/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 8/20 | 1.00 |
| ▸ | FLT3 | P36888 | 6/20 | 0.82 |
| ▸ | CDK2 | P24941 | 3/20 | 0.73 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.73 |
| ▸ | CDK4 | P11802 | 2/20 | 0.73 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.73 |
| ▸ | CCND1 | P24385 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | CDK14 | O94921 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | SRC | P12931 | 1/20 | 0.73 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.73 |
| ▸ | CDK11B | P21127 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30597674 | 0.85 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30094663 | 0.85 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30319807 | 0.85 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL29421607 | 0.84 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30597663 | 0.82 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL29648491 | 0.78 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30273058 | 0.78 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30597665 | 0.78 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30319763 | 0.77 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30380971 | 0.77 | GSK3A (0.70) | GSK3AGSK3BCDK5CDK5R1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466342-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | Institut Pasteur (FR) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139242-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | INSTITUT PASTEUR (FR) | 2023-07-27 | — | — | WO | disclosed |