Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 4/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979721 | 1.00 | MAT2A (0.39) | MAT2ATACR2TACR1MKNK1MKNK2 | |
| SCHEMBL22979151 | 0.90 | MKNK1 (0.37) | MKNK1MKNK2ADORA2AADORA1GBA1 | |
| SCHEMBL31149956 | 0.90 | MKNK1 (0.37) | MKNK1MKNK2ADORA2AADORA1GBA1 | |
| SCHEMBL22988329 | 0.88 | GBA1 (0.44) | MKNK1MKNK2ADORA2AADORA1GBA1 | |
| SCHEMBL30393088 | 0.88 | GBA1 (0.44) | MKNK1MKNK2ADORA2AADORA1GBA1 | |
| SCHEMBL29648821 | 0.87 | TACR2 (0.41) | TACR2TACR1ADORA2AADORA1 | |
| SCHEMBL22980986 | 0.87 | TACR2 (0.41) | TACR2TACR1ADORA2AADORA1 | |
| SCHEMBL22979759 | 0.87 | HPGDS (0.39) | MKNK1MKNK2ADORA2AADORA1 | |
| SCHEMBL29648542 | 0.87 | HPGDS (0.39) | MKNK1MKNK2ADORA2AADORA1 | |
| SCHEMBL22979756 | 0.83 | ADORA3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |