SCHEMBL29649161

SCHEMBL29649161

FC(F)(F)C(F)(F)N1CCNCC1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 3/20 0.34
EPHX2 P34913 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HTR3E A5X5Y0 2/20 0.31
HTR3B O95264 2/20 0.31
HTR3A P46098 2/20 0.31
HTR3D Q70Z44 2/20 0.31
HTR3C Q8WXA8 2/20 0.31
SIGMAR1 Q99720 2/20 0.31
LMNA P02545 1/20 0.31
HTR1D P28221 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1219179 0.80 ADRB1 (0.31) ADRB1
SCHEMBL517802 0.77 ADRB1 (0.37) ADRB1EPHX2ALDH1A1HTR3EHTR3B
SCHEMBL26646496 0.74 ADRB1 (0.35) ADRB1ALDH1A1HTR3EHTR3BHTR3A
Hydrochloric Acid SCHEMBL12818396 0.74 ALDH1A1 (0.37) ADRB1ALDH1A1HTR3EHTR3BHTR3A
SCHEMBL20699458 0.73 CYP2B6 (0.31)
SCHEMBL28311781 0.72 ADRB1 (0.34) ADRB1ALDH1A1HTR3EHTR3BHTR3A
Hydrazine SCHEMBL27569857 0.72 ADRB1 (0.34) ADRB1ALDH1A1HTR3EHTR3BHTR3A
SCHEMBL15313178 0.72 ADRB1 (0.34) ADRB1ALDH1A1HTR3EHTR3BHTR3A
Benzene SCHEMBL27534755 0.70 SIGMAR1 (0.39) ADRB1EPHX2ALDH1A1HTR3EHTR3B
SCHEMBL918508 0.69 ALDH1A1 (0.43) ADRB1EPHX2ALDH1A1HTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108713018-B Amine-containing cyclic hydrofluoroethers and methods of use thereof 3M创新有限公司 2022-07-05 CN disclosed