Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681497 | 1.00 | SPHK1 (0.45) | SPHK1LTA4HSPHK2KIF11ALDH1A1 | |
| SCHEMBL18388780 | 0.89 | LTA4H (0.48) | SPHK1LTA4HKIF11CASR | |
| SCHEMBL25223009 | 0.89 | LTA4H (0.48) | SPHK1LTA4HKIF11CASR | |
| SCHEMBL25364554 | 0.87 | SIRT1 (0.41) | ALDH1A1MAPK1NPSR1 | |
| SCHEMBL25364561 | 0.87 | SIRT1 (0.41) | ALDH1A1MAPK1NPSR1 | |
| SCHEMBL29649439 | 0.86 | MAPK1 (0.39) | MAPK1NPSR1 | |
| SCHEMBL29649503 | 0.86 | ALDH1A1 (0.44) | LTA4HKIF11ALDH1A1MAPK1 | |
| SCHEMBL29649482 | 0.85 | LTA4H (0.41) | SPHK1LTA4HKIF11ALDH1A1CASR | |
| SCHEMBL29602479 | 0.83 | LTA4H (0.43) | SPHK1LTA4HSPHK2KIF11 | |
| SCHEMBL26686610 | 0.83 | LTA4H (0.43) | SPHK1LTA4HSPHK2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237008-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | Elucida Oncology, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093800-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. (US) | 2022-05-05 | — | — | WO | disclosed |