Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 3/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26026727 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2ADAM10MMP2MMP9MMP12 | |
| SCHEMBL25357504 | 0.89 | SIRT1 (0.41) | SMN1; SMN2ADAM10MMP2MMP9MMP12 | |
| SCHEMBL25357515 | 0.89 | SIRT1 (0.41) | SMN1; SMN2ADAM10MMP2MMP9MMP12 | |
| SCHEMBL26026883 | 0.88 | SIRT1 (0.38) | SIRT1SIRT2MAPTHTTCA1 | |
| SCHEMBL29649497 | 0.88 | SIRT1 (0.43) | ADAM10MMP2MMP9MMP12MMP14 | |
| SCHEMBL21597895 | 0.87 | SIRT2 (0.37) | SMN1; SMN2SIRT1SIRT2NPC1RAB9A | |
| SCHEMBL21597894 | 0.87 | SIRT2 (0.37) | SMN1; SMN2SIRT1SIRT2NPC1RAB9A | |
| SCHEMBL23962289 | 0.85 | MAPT (0.47) | SMN1; SMN2SIRT1MAPTHTTALDH1A1 | |
| SCHEMBL26026725 | 0.84 | LTA4H (0.42) | SMN1; SMN2ADAM10MMP2MMP9MMP12 | |
| SCHEMBL21859193 | 0.82 | PLAU (0.42) | SMN1; SMN2MMP2SIRT1SIRT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237008-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | Elucida Oncology, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093800-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. (US) | 2022-05-05 | — | — | WO | disclosed |