Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 3/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649566 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2ADAM10MMP2MMP9MMP12 | |
| SCHEMBL25357504 | 0.89 | SIRT1 (0.41) | SMN1; SMN2ADAM10MMP2MMP9MMP12 | |
| SCHEMBL25357515 | 0.89 | SIRT1 (0.41) | SMN1; SMN2ADAM10MMP2MMP9MMP12 | |
| SCHEMBL26026883 | 0.88 | SIRT1 (0.38) | SIRT1SIRT2MAPTHTTCA1 | |
| SCHEMBL29649497 | 0.88 | SIRT1 (0.43) | ADAM10MMP2MMP9MMP12MMP14 | |
| SCHEMBL21597895 | 0.87 | SIRT2 (0.37) | SMN1; SMN2SIRT1SIRT2NPC1RAB9A | |
| SCHEMBL21597894 | 0.87 | SIRT2 (0.37) | SMN1; SMN2SIRT1SIRT2NPC1RAB9A | |
| SCHEMBL23962289 | 0.85 | MAPT (0.47) | SMN1; SMN2SIRT1MAPTHTTALDH1A1 | |
| SCHEMBL26026725 | 0.84 | LTA4H (0.42) | SMN1; SMN2ADAM10MMP2MMP9MMP12 | |
| SCHEMBL21859193 | 0.82 | PLAU (0.42) | SMN1; SMN2MMP2SIRT1SIRT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241243-A1 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230241243-A1 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | NDC1, KIFC1, SDCBP | SMN1; SMN2 1162/4885ADAM10 1951/4885MMP2 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.