Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29650273 | 1.00 | CETP (0.51) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL27851258 | 1.00 | CETP (0.51) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL27729776 | 1.00 | CETP (0.51) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL28547677 | 1.00 | CETP (0.51) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL29160806 | 0.99 | CETP (0.50) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL29650278 | 0.99 | CETP (0.50) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL29160910 | 0.99 | CETP (0.50) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL3247583 | 0.98 | ALDH1A1 (0.51) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL4060020 | 0.97 | ALDH1A1 (0.50) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL3823743 | 0.94 | CA2 (0.53) | CETPALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563103-B | Modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2022-05-27 | — | — | CN | disclosed |