Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729776 | 0.98 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL28547677 | 0.98 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL29650322 | 0.98 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL4060020 | 0.98 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL27851258 | 0.98 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL29650273 | 0.98 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL29160806 | 0.97 | CETP (0.50) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL29160910 | 0.97 | CETP (0.50) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL29650278 | 0.97 | CETP (0.50) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL3823743 | 0.95 | CA2 (0.53) | ALDH1A1CYP3A4TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865876-A | Method for preparing ramipril intermediate | 浙江华海药业股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117865876-A | Method for preparing ramipril intermediate | 浙江华海药业股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117865876-A | Method for preparing ramipril intermediate | 浙江华海药业股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114057740-B | Spiropyrimidinone derivatives, method for the production thereof, pharmaceutical compositions and use thereof | 上海赛默罗生物科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117500499-A | Substituted indole compounds and methods of use thereof | 奇努克治疗公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117050086-A | Pyrimidinone pyrazolo compound containing fused ring group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-116745277-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-09-12 | — | — | CN | disclosed |
| CN-111808105-B | Pyrimidinone pyrazolo compound containing fused ring group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-109563043-B | Substituted pyridines as inhibitors of DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-05-31 | — | — | CN | disclosed |
| EP-2183246-A2 | 2-AZA-BICYCLO-[3.3.0]-OCTANE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009122433-A2 | A PROCESS FOR PREPARATION OF RAMIPRIL | IPCA LABORATORIES LIMITED (IN) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009016564-A2 | 2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-02-05 | — | — | WO | disclosed |
| EP-1709044-A2 | OXAZOLIDINONE-QUINOLONE HYBRID ANTIBIOTICS | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2006-10-11 | — | — | EP | disclosed |
| WO-2006059347-A3 | IMPROVED PROCESS FOR PREPARATION OF RAMIPRIL | MOREPEN LAB LTD (IN) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006059347-A2 | IMPROVED PROCESS FOR PREPARATION OF RAMIPRIL | MOREPEN LABORATORIES LIMITED (IN) | 2006-06-08 | — | — | WO | disclosed |
| WO-2006059347-A2 | IMPROVED PROCESS FOR PREPARATION OF RAMIPRIL | MOREPEN LABORATORIES LIMITED (IN) | 2006-06-08 | — | — | WO | disclosed |
| EP-1620098-A1 | USE OF OXAZOLIDINONE-QUINOLINE HYBRID ANTIBIOTICS FOR THE TREATMENT OF ANTHRAX AND OTHER INFECTIONS | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2006-02-01 | — | — | EP | disclosed |
| WO-2005058888-A2 | OXAZOLIDINONE-QUINOLONE HYBRID ANTIBIOTICS | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2005-06-30 | — | — | WO | disclosed |
| WO-2004096221-A1 | USE OF OXAZOLIDINONE-QUINOLINE HYBRID ANTIBIOTICS FOR THE TREATMENT OF ANTHRAX AND OTHER INFECTIONS | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-11-11 | — | — | WO | disclosed |