Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359356 | 1.00 | PSMB8 (0.45) | PSMB8ADORA1ADORA3PARP1RPS6KA3 | |
| SCHEMBL3942822 | 0.78 | MAPKAPK2 (0.46) | PARP1RPS6KA3CHEK1MAPKAPK2CSNK2A1 | |
| SCHEMBL21530547 | 0.78 | PARP1 (0.42) | PARP1RPS6KA3EGLN1MAPKAPK2CSNK2A1 | |
| SCHEMBL26111670 | 0.78 | NOS1 (0.39) | PSMB8PARP1RPS6KA3PDGFRBFGFR1 | |
| SCHEMBL1041260 | 0.78 | KDM4E (0.42) | PARP1RPS6KA3MAPKAPK2CSNK2A1PLK3 | |
| SCHEMBL30196908 | 0.78 | PARP1 (0.42) | PARP1RPS6KA3EGLN1MAPKAPK2CSNK2A1 | |
| SCHEMBL30592183 | 0.78 | NOS1 (0.39) | PSMB8PARP1RPS6KA3PDGFRBFGFR1 | |
| SCHEMBL16671449 | 0.78 | MAPKAPK2 (0.42) | PARP1RPS6KA3MAPKAPK2CSNK2A1PLK3 | |
| SCHEMBL13723653 | 0.78 | ADORA3 (0.44) | ADORA1ADORA3PARP1AURKAGABRP | |
| SCHEMBL9037873 | 0.74 | HTT (0.49) | ADORA1ADORA3RPS6KA3EGLN1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483421-B | Preparation method of quinoxalinone derivative | 沈阳师范大学 | 2022-06-10 | — | — | CN | disclosed |