Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.50 |
| ▸ | PGR | P06401 | 7/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851614 | 1.00 | NR3C1 (0.50) | NR3C1PGRNR3C2ALDH1A1MEN1 | |
| SCHEMBL8653902 | 0.85 | PDE5A (0.47) | NR3C1PGRNR3C2ALDH1A1POLB | |
| SCHEMBL19585644 | 0.81 | NR3C1 (0.44) | NR3C1PGRNR3C2ALDH1A1MAPK1 | |
| SCHEMBL18926938 | 0.80 | SMN1; SMN2 (0.47) | NR3C1PGRNR3C2ALDH1A1MAPK1 | |
| SCHEMBL29696630 | 0.79 | HTR6 (0.55) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL31174785 | 0.79 | NR3C1 (0.46) | NR3C1PGRNR3C2ALDH1A1MAPK1 | |
| SCHEMBL17111036 | 0.79 | HTR6 (0.55) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4886606 | 0.78 | MEN1 (0.49) | NR3C1PGRNR3C2ALDH1A1MEN1 | |
| SCHEMBL29035965 | 0.78 | NR3C1 (0.43) | NR3C1PGRNR3C2ALDH1A1MEN1 | |
| SCHEMBL7207556 | 0.78 | NR3C1 (0.42) | NR3C1PGRNR3C2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699189-B | Modulators of beta-3 adrenergic receptors useful for treating or preventing heart failure and disorders associated therewith | 艾尼纳制药公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-109563103-B | Modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2022-05-27 | — | — | CN | disclosed |