SCHEMBL29652519

SCHEMBL29652519

CCc1ccc(OC)c(S(=O)(=O)N(OCc2ccc(OC)cc2OC)c2noc3c(C(=O)NC)cccc23)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GALR3 O60755 2/20 0.38
▸ KMT2A Q03164 4/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ TSHR P16473 2/20 0.37
▸ HTT P42858 2/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ MAPT P10636 3/20 0.36
▸ PTK2 Q05397 1/20 0.35
▸ MTNR1A P48039 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ TAS1R3 Q7RTX0 1/20 0.34
▸ TAS1R1 Q7RTX1 1/20 0.34
▸ NR2F2 P24468 1/20 0.34
▸ AKR1C3 P42330 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21596872 1.00 GALR3 (0.38) GALR3KMT2AMEN1TSHRHTT
SCHEMBL31605552 0.93 MAPT (0.38) GALR3KMT2AMEN1TSHRHTT
SCHEMBL21596821 0.93 MAPT (0.38) GALR3KMT2AMEN1TSHRHTT
SCHEMBL21596809 0.86 MAPT (0.36) KMT2AMEN1TSHRHTTMAPK1
SCHEMBL29652454 0.86 MAPT (0.36) KMT2AMEN1TSHRHTTMAPK1
SCHEMBL29652522 0.84 ALDH1A1 (0.32) KMT2AMEN1TSHRHTTMAPK1
SCHEMBL28906747 0.84 ALDH1A1 (0.32) KMT2AMEN1TSHRHTTMAPK1
SCHEMBL28507830 0.84 KAT7 (0.33) KMT2AMEN1TSHRHTTMAPK1
SCHEMBL29652540 0.84 KAT7 (0.33) KMT2AMEN1TSHRHTTMAPK1
SCHEMBL28512950 0.80 CCNA2 (0.36) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 — — CN disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 — — EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 GALR3 3288/4885KMT2A 4165/4885MEN1 122/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B GALR3 926/4885KMT2A 890/4885MEN1 866/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 GALR3 3282/4885KMT2A 4165/4885MEN1 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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