Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | KAT7 | O95251 | 2/20 | 0.33 |
| ▸ | KAT6B | Q8WYB5 | 2/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31605552 | 1.00 | MAPT (0.38) | MAPTTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL21596872 | 0.93 | GALR3 (0.38) | MAPTTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL29652519 | 0.93 | GALR3 (0.38) | MAPTTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL21596809 | 0.88 | MAPT (0.36) | MAPTTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL29652454 | 0.88 | MAPT (0.36) | MAPTTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL28906747 | 0.86 | ALDH1A1 (0.32) | MAPTTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL29652522 | 0.86 | ALDH1A1 (0.32) | MAPTTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL28507830 | 0.86 | KAT7 (0.33) | MAPTTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL29652540 | 0.86 | KAT7 (0.33) | MAPTTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL29652513 | 0.82 | CCNA2 (0.36) | KDM4EKAT7KAT6BKAT6AKAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4335439-A2 | COMPOUNDS | CTXT PTY LTD (AU) | 2024-03-13 | — | — | EP | disclosed |
| EP-3810602-B1 | COMPOUNDS | CTXT PTY LTD (AU) | 2023-11-01 | — | — | EP | disclosed |
| US-20220153710-A1 | Compounds | CTXT PTY LTD (AU) | 2022-05-19 | — | — | US | disclosed |
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| US-20200039945-A1 | Compounds | CTXT PTY LIMITED (AU) | 2020-02-06 | — | — | US | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |
| US-20160207949-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION TO A CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153710-A1 | Compounds | SLC10A1, ABCB11, PCSK9 | MAPT 1135/4885TSHR 3584/4885ALDH1A1 981/4885 |
| US-20200039945-A1 | Compounds | SLC10A1, ABCB11, PCSK9 | MAPT 1136/4885TSHR 3583/4885ALDH1A1 982/4885 |
| US-20160207949-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION TO A CELL BINDING MOLECULE | PDCD5, CD4, PDCD6 | MAPT 4035/4885TSHR 1121/4885ALDH1A1 1947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.