Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29334037 | 0.88 | MAPT (0.53) | KCNH2KCNJ1ALDH1A1POLBLMNA | |
| SCHEMBL29337401 | 0.86 | CNR2 (0.56) | KCNH2KCNJ1ALDH1A1POLBLMNA | |
| SCHEMBL3162128 | 0.84 | KCNH2 (0.63) | KCNH2KCNJ1ALDH1A1POLBLMNA | |
| Hydrochloric Acid SCHEMBL10919667 | 0.84 | KCNH2 (0.51) | KCNH2KCNJ1ALDH1A1POLBLMNA | |
| SCHEMBL6233097 | 0.83 | APLNR (0.53) | ALDH1A1LMNAMAPT | |
| SCHEMBL17817840 | 0.80 | ALDH1A1 (0.61) | KCNH2KCNJ1ALDH1A1POLBLMNA | |
| SCHEMBL17817839 | 0.80 | ALDH1A1 (0.61) | KCNH2KCNJ1ALDH1A1POLBLMNA | |
| SCHEMBL15746105 | 0.80 | ALDH1A1 (0.61) | KCNH2KCNJ1ALDH1A1POLBLMNA | |
| SCHEMBL14880488 | 0.80 | KCNJ1 (0.63) | KCNH2KCNJ1ALDH1A1POLBLMNA | |
| SCHEMBL492221 | 0.80 | APP (0.70) | KCNH2KCNJ1ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109492-A1 | PYRROLOPYRIDAZINE COMPOUNDS AS KINASE INHIBITORS | GOSSAMER BIOSERVICES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |