Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | PRKCI | P41743 | 3/20 | 0.31 |
| ▸ | APP | P05067 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23513933 | 1.00 | NUDT1 (0.33) | NUDT1PRKCIAPPHSD17B10 | |
| SCHEMBL23514158 | 0.80 | TLR7 (0.45) | APP | |
| SCHEMBL29653636 | 0.80 | TLR7 (0.45) | APP | |
| SCHEMBL23513867 | 0.78 | APP (0.50) | APP | |
| SCHEMBL29653626 | 0.78 | APP (0.50) | APP | |
| SCHEMBL23513935 | 0.78 | PRKCI (0.34) | PRKCIAPP | |
| SCHEMBL29653633 | 0.78 | PRKCI (0.34) | PRKCIAPP | |
| SCHEMBL23513936 | 0.77 | NLRP3 (0.43) | PRKCI | |
| SCHEMBL23500163 | 0.74 | NPC1 (0.40) | PRKCIAPP | |
| SCHEMBL23500158 | 0.74 | NPC1 (0.40) | PRKCIAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555565-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |