Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654261 | 0.78 | MPL (0.53) | HTR2CTGFBR1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL713110 | 0.78 | HSD17B10 (0.61) | HTR2CTGFBR1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL28225169 | 0.78 | PDE10A (0.54) | HTR2CTGFBR1DHFRHSD17B10ALDH1A1 | |
| Bromide SCHEMBL8357463 | 0.76 | HSD17B10 (0.59) | HTR2CTGFBR1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL11454418 | 0.76 | KMT2A (0.59) | HSD17B10ALDH1A1HPGDCYP3A4KDM4E | |
| SCHEMBL28988200 | 0.76 | ALDH1A1 (0.41) | TGFBR1DHFRHSD17B10ALDH1A1HPGD | |
| SCHEMBL9830640 | 0.76 | HTR2B (0.60) | HSD17B10ALDH1A1HPGDTSHRLMNA | |
| SCHEMBL9830414 | 0.76 | ATP4A (0.44) | DHFRHSD17B10ALDH1A1TSHRKDM4E | |
| SCHEMBL7570173 | 0.74 | ALDH1A1 (0.66) | HTR2CHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL16516559 | 0.74 | ALOX15 (0.50) | HTR2CHSD17B10ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |