Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 1.00 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 1.00 |
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | CA7 | P43166 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25954216 | 0.92 | PDCD1 (0.85) | PDCD1CD274CA12CA1CA2 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL27592410 | 0.88 | PDCD1 (0.78) | PDCD1CD274CA12CA1CA2 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL96918 | 0.88 | PDCD1 (0.78) | PDCD1CD274CA12CA1CA2 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL29019189 | 0.86 | PDCD1 (0.75) | PDCD1CD274CA12CA1CA2 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL28432759 | 0.86 | PDCD1 (0.75) | PDCD1CD274CA12CA1CA2 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL8381956 | 0.86 | PDCD1 (0.75) | PDCD1CD274CA12CA1CA2 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL9343935 | 0.86 | PDCD1 (0.75) | PDCD1CD274CA12CA1CA2 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL31017505 | 0.86 | PDCD1 (0.75) | PDCD1CD274CA12CA1CA2 | |
| SCHEMBL701832 | 0.85 | CA12 (0.83) | PDCD1CD274CA12CA1CA2 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL28356777 | 0.85 | PDCD1 (0.74) | PDCD1CD274CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| US-10954267-B2 | Dipeptide comprising a non-proteogenic amino acid | NOVO NORDISK A/S (DK) | 2021-03-23 | — | — | US | claimed |
| US-20190002496-A1 | Dipeptide Comprising a Non-Proteogenic Amino Acid | NOVO NORDISK AS (DK) | 2019-01-03 | — | — | US | claimed |
| EP-2914256-A1 | DISUBSTITUTED AMINO ACIDS AND METHODS OF PREPARATION AND USE THEREOF | Aileron Therapeutics, Inc. (US) | 2015-09-09 | — | — | EP | claimed |
| US-20140364587-A1 | Dipeptide Comprising a Non-Proteogenic Amino Acid | NOVO NORDISK A/S (DK) | 2014-12-11 | — | — | US | claimed |
| US-20140128581-A1 | DISUBSTITUTED AMINO ACIDS AND METHODS OF PREPARATION AND USE THEREOF | AILERON THERAPEUTICS, INC. (US) | 2014-05-08 | — | — | US | claimed |
| WO-2014071241-A1 | DISUBSTITUTED AMINO ACIDS AND METHODS OF PREPARATION AND USE THEREOF | AILERON THERAPEUTICS, INC. (US) | 2014-05-08 | — | — | WO | claimed |
| US-6770436-B1 | RADIATION-ACTIVATED CATALYSTS (RACS), AUTOCATALYTIC REACTIONS, AND PROTECTIVE GROUPS ARE EMPLOYED TO ACHIEVE A HIGHLY SENSITIVE, HIGH RESOLUTION, RADIATION DIRECTED COMBINATORIAL SYNTHESIS OF PATTERN ARRAYS OF DIVERSE POLYMERS | AFFYMETRIX, INC. | 2004-08-03 | — | — | US | claimed |
| US-6083697-A | Chemical amplification for the synthesis of patterned arrays | AFFYMETRIX, INC. (US) | 2000-07-04 | — | — | US | claimed |
| US-4855486-A | Blocked, marked amino acids | KALBAG SURESH M (US) | 1989-08-08 | — | — | US | claimed |
| EP-0292228-A2 | Protecting groups for asparagine and glutamine in peptide synthesis | MILLIPORE CORPORATION (US) | 1988-11-23 | — | — | EP | claimed |
| US-4755558-A | Using internal marker | BECKMAN INSTRUMENTS, INC. (US) | 1988-07-05 | — | — | US | claimed |
| CN-119504433-A | Carboxylic acid esterification method | 国网安徽省电力有限公司电力科学研究院 | 2025-02-25 | — | — | CN | disclosed |
| CN-118324762-A | Compounds and compositions for treating CNS disorders | 布鲁奥科制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240218014-A1 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-04 | — | — | US | disclosed |
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | disclosed |
| EP-0001295-A2 | Somatostatin-like cyclopeptides, a process for their preparation, pharmaceutical compositions containing them, and their therapeutical application | CIBA-GEIGY AG (CH) | 1979-04-04 | — | — | EP | disclosed |
| US-4066635-A | ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-3963691-A | POLYPEPTIDES, PEPTIZATION | MERCK & CO., INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3862113-A | PROCESS FOR THE SELECTIVE ELIMINATION OF ARALKYLOXYCARBONYL AND TRITYL N-PROTECTING GROUPS WITH 2,2,2-TRIFLUOROETHANOL | CIBA GEIGY CORP | 1975-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240218014-A1 | SYNTHESIS OF A CYCLIC PEPTIDE | VIP, QPCT, PTMS | PDCD1 3590/4885CD274 4721/4885CA12 1550/4885 |
| US-20140364587-A1 | Dipeptide Comprising a Non-Proteogenic Amino Acid | DNPEP, ANPEP, NPEPPS | PDCD1 2421/4885CD274 4473/4885CA12 1779/4885 |
| US-10954267-B2 | Dipeptide comprising a non-proteogenic amino acid | DNPEP, ANPEP, NPEPPS | PDCD1 2421/4885CD274 4473/4885CA12 1779/4885 |
| US-20140128581-A1 | DISUBSTITUTED AMINO ACIDS AND METHODS OF PREPARATION AND USE THEREOF | ASNS, BCAT1, BCAT2 | PDCD1 1615/4885CD274 3299/4885CA12 663/4885 |
| US-20190002496-A1 | Dipeptide Comprising a Non-Proteogenic Amino Acid | DNPEP, ANPEP, NPEPPS | PDCD1 2421/4885CD274 4473/4885CA12 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.