SCHEMBL29655015

SCHEMBL29655015

N[C@]1(OP(=O)(O)O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PYGB P11216 8/20 0.40
PYGL P06737 3/20 0.39
PYGM P11217 2/20 0.39
FBP1 P09467 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28613795 0.79 ADSS2 (0.51) FBP1
SCHEMBL28851205 0.79 PYGB (0.40) PYGBPYGLPYGMFBP1
SCHEMBL28279797 0.79 PYGB (0.40) PYGBPYGLPYGMFBP1
SCHEMBL515356 0.79 PYGB (0.40) PYGBPYGLPYGMFBP1
SCHEMBL4312544 0.77 PYGB (0.40) PYGBPYGLPYGM
SCHEMBL28285579 0.75 PYGB (0.42) PYGBPYGLPYGMFBP1
Sulfuric Acid SCHEMBL29192736 0.74 PYGB (0.36) PYGBPYGLPYGMFBP1
SCHEMBL23111917 0.73 ADSS2 (0.35) PYGBPYGLPYGMFBP1
SCHEMBL1932762 0.73 ADSS2 (0.35) PYGBPYGLPYGMFBP1
SCHEMBL28991003 0.73 ADSS2 (0.35) PYGBPYGLPYGMFBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243934-A2 METHOD FOR TREATING AMYLOIDOGENIC DISEASE National Health Research Institutes (TW) 2023-09-20 EP disclosed
WO-2022104088-A2 METHOD FOR TREATING AMYLOIDOGENIC DISEASE NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2022-05-19 WO disclosed