SCHEMBL515356

SCHEMBL515356

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nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PYGB P11216 8/20 0.40
PYGL P06737 3/20 0.40
PYGM P11217 2/20 0.40
FBP1 P09467 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28851205 1.00 PYGB (0.40) PYGBPYGLPYGMFBP1MEN1
SCHEMBL28279797 1.00 PYGB (0.40) PYGBPYGLPYGMFBP1MEN1
SCHEMBL1932762 0.95 ADSS2 (0.35) PYGBPYGLPYGMFBP1MEN1
SCHEMBL28991003 0.95 ADSS2 (0.35) PYGBPYGLPYGMFBP1MEN1
SCHEMBL23111917 0.95 ADSS2 (0.35) PYGBPYGLPYGMFBP1MEN1
Sulfuric Acid SCHEMBL29192736 0.94 PYGB (0.36) PYGBPYGLPYGMFBP1MEN1
SCHEMBL8838940 0.85 FBP1 (0.36) FBP1
SCHEMBL4312544 0.79 PYGB (0.40) PYGBPYGLPYGM
SCHEMBL29655015 0.79 PYGB (0.40) PYGBPYGLPYGMFBP1
SCHEMBL10385012 0.78 PYGB (0.42) PYGBPYGLPYGMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9694111-B2 Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent LUTONIX, INC. (US) 2017-07-04 US claimed
US-20160250386-A1 MEDICAL DEVICE RAPID DRUG RELEASING COATINGS COMPRISING A THERAPEUTIC AGENT AND A CONTRAST AGENT LUTONIX INC (US) 2016-09-01 US claimed
US-9248220-B2 Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent LUTONIX, INC. (US) 2016-02-02 US claimed
US-20150093337-A1 MEDICAL DEVICE RAPID DRUG RELEASING COATINGS COMPRISING A THERAPEUTIC AGENT AND A CONTRAST AGENT LUTONIX INC (US) 2015-04-02 US claimed
US-8932561-B2 Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent LUTONIX, INC. (US) 2015-01-13 US claimed
US-8425459-B2 Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent LUTONIX, INC. (US) 2013-04-23 US claimed
JP-2010540159-A 2010-12-24 JP claimed
EP-2073860-A1 DRUG RELEASING COATINGS FOR MEDICAL DEVICES Lutonix, Inc. (US) 2009-07-01 EP claimed
WO-2009051614-A1 DRUG RELEASING COATINGS FOR MEDICAL DEVICES LUTONIX, INC. (US) 2009-04-23 WO claimed
US-20080255508-A1 Such as balloon and stents; medical device with overcoating of drug with additive; bioavailability LUTONIX, INC. 2008-10-16 US claimed
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP disclosed
US-12605342-B2 Polymer-encapsulated drug particles TONIC MEDICAL, INC. (US) 2026-04-21 US disclosed
US-12576037-B2 Polymer-encapsulated drug particles TONIC MEDICAL, INC. (US) 2026-03-17 US disclosed
EP-4106828-B1 POLYMER-ENCAPSULATED DRUG PARTICLES TONIC MEDICAL INC (US) 2026-03-11 EP disclosed
EP-4678198-A2 POLYMER-ENCAPSULATED DRUG PARTICLES Tonic Medical, Inc. (US) 2026-01-14 EP disclosed
US-20080255509-A1 MEDICAL DEVICE RAPID DRUG RELEASING COATINGS COMPRISING OILS, FATTY ACIDS, AND/OR LIPIDS LUTONIX, INC. 2008-10-16 US disclosed
US-20080255508-A1 Such as balloon and stents; medical device with overcoating of drug with additive; bioavailability LUTONIX, INC. 2008-10-16 US disclosed
US-20080255510-A1 Layer containing therapeutic agent, adjuvant and contrast agent ; high speed supplying agent to tissue; adjuvant contains hyfrophilic part and drug affinity part; overcoating exterior surface of medical device LUTONIX, INC. 2008-10-16 US disclosed
US-7102023-B2 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-09-05 US disclosed
US-20040220389-A1 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576037-B2 Polymer-encapsulated drug particles PHOSPHO1, SGMS1, SGMS2 PYGB 3445/4885PYGL 2617/4885PYGM 1986/4885
US-20040220389-A1 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries FUT5, FUT6, UGCG PYGB 1862/4885PYGL 1969/4885PYGM 3828/4885
US-12605342-B2 Polymer-encapsulated drug particles MUC1, SLC10A2, EGFR PYGB 3917/4885PYGL 2421/4885PYGM 2552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.