SCHEMBL29655260

SCHEMBL29655260

CC(C)C[C@H](NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 9/20 0.63
DPP4 P27487 1/20 0.54
DPP8 Q6V1X1 1/20 0.54
DPP9 Q86TI2 1/20 0.54
BACE1 P56817 9/20 0.50
NAALAD2 Q9Y3Q0 2/20 0.50
BACE2 Q9Y5Z0 2/20 0.50
RIMKLA Q8IXN7 1/20 0.49
CTSD P07339 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30430488 0.99 FOLH1 (0.61) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL30480113 0.99 FOLH1 (0.61) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL31195712 0.95 FOLH1 (0.60) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL29796607 0.95 FOLH1 (0.60) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL30784907 0.95 FOLH1 (0.60) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL30473801 0.95 FOLH1 (0.57) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL4218275 0.94 FOLH1 (0.63) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL29400510 0.94 FOLH1 (0.63) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL30193377 0.94 FOLH1 (0.63) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL30553677 0.94 FOLH1 (0.63) FOLH1DPP4DPP8DPP9BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836724-B Soy sauce rich in salty peptide and preparation method thereof 佛山市海天(高明)调味食品有限公司 2024-05-31 CN disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
CN-117264969-A 84K poplar PagGRF20 gene and application thereof 北京林业大学 2023-12-22 CN disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
CN-115747225-A Populus deltoides PdbGRF1 gene and application thereof 东北林业大学 2023-03-07 CN disclosed
US-20220361545-A1 ENHANCED SALT COMPOSITIONS AND METHODS OF PREPARATION THEREOF DOUXMATOK LTD (IL) 2022-11-17 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 FOLH1 1289/4885DPP4 743/4885DPP8 1035/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 FOLH1 1289/4885DPP4 743/4885DPP8 1035/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 FOLH1 1289/4885DPP4 743/4885DPP8 1035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.