SCHEMBL29796607

SCHEMBL29796607

CC(C)C[C@H](NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@H](CC(C)C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 8/20 0.60
DPP4 P27487 1/20 0.55
DPP8 Q6V1X1 1/20 0.55
DPP9 Q86TI2 1/20 0.55
BACE1 P56817 9/20 0.49
CTSD P07339 2/20 0.49
ALDH1A1 P00352 1/20 0.49
BACE2 Q9Y5Z0 2/20 0.48
NAALAD2 Q9Y3Q0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31195712 1.00 FOLH1 (0.60) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL30784907 1.00 FOLH1 (0.60) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL30676233 0.97 FOLH1 (0.64) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL537147 0.97 FOLH1 (0.64) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL537148 0.97 FOLH1 (0.64) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL31233849 0.96 FOLH1 (0.56) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL29655260 0.95 FOLH1 (0.63) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL29400510 0.95 FOLH1 (0.63) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL30480113 0.94 FOLH1 (0.61) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL30430488 0.94 FOLH1 (0.61) FOLH1DPP4DPP8DPP9BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220280579-A1 Formulations for Prevention or Reduction of C. Difficile Infections SPOREGEN LIMITED (GB) 2022-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220280579-A1 Formulations for Prevention or Reduction of C. Difficile Infections SI, FABP2, CRY1 FOLH1 2799/4885DPP4 1345/4885DPP8 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.