SCHEMBL29655310

SCHEMBL29655310

CC=CN(Cl)[13c]1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
RELA Q04206 1/20 0.31
ALDH1A1 P00352 5/20 0.31
NPSR1 Q6W5P4 2/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
RAB9A P51151 1/20 0.30
FAAH O00519 1/20 0.30
PHGDH O43175 1/20 0.30
MGLL Q99685 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8076654 0.75 MEN1 (0.37) HTTKMT2AMEN1CA12CA1
SCHEMBL8076656 0.75 MEN1 (0.37) HTTKMT2AMEN1CA12CA1
SCHEMBL9238361 0.75 MEN1 (0.37) HTTKMT2AMEN1CA12CA1
SCHEMBL17436357 0.73 MEN1 (0.41) HTTKMT2AMEN1CA12CA1
SCHEMBL8559716 0.73 MEN1 (0.41) HTTKMT2AMEN1CA12CA1
SCHEMBL8559720 0.73 MEN1 (0.41) HTTKMT2AMEN1CA12CA1
SCHEMBL3155192 0.70 ALDH1A1 (0.39) HTTKMT2AMEN1CA12CA1
SCHEMBL6872360 0.70 CA12 (0.37) HTTKMT2AMEN1CA12CA1
SCHEMBL18812 0.70
Benzene SCHEMBL27358958 0.70 ALDH1A1 (0.41) HTTKMT2AMEN1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113620811-B Halogenation method of aromatic compound 中国科学院兰州化学物理研究所 2022-05-24 CN disclosed