SCHEMBL8559716

SCHEMBL8559716

C/C=C\N(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HTT P42858 1/20 0.41
ALDH1A1 P00352 4/20 0.38
ALOX15 P16050 3/20 0.38
HSD17B10 Q99714 3/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 2/20 0.37
RELA Q04206 1/20 0.37
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
CA12 O43570 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
FAAH O00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17436357 1.00 MEN1 (0.41) MEN1KMT2AHTTALDH1A1ALOX15
SCHEMBL8559720 1.00 MEN1 (0.41) MEN1KMT2AHTTALDH1A1ALOX15
SCHEMBL7053933 0.79 MEN1 (0.44) MEN1KMT2AHTTALDH1A1ALOX15
SCHEMBL8076656 0.77 MEN1 (0.37) MEN1KMT2AHTTALDH1A1ALOX15
SCHEMBL8076654 0.77 MEN1 (0.37) MEN1KMT2AHTTALDH1A1ALOX15
SCHEMBL9238361 0.77 MEN1 (0.37) MEN1KMT2AHTTALDH1A1ALOX15
SCHEMBL10628459 0.76 RELA (0.54) MEN1KMT2AHTTALDH1A1MAPT
SCHEMBL6030728 0.76 APP (0.47) MEN1KMT2AALDH1A1ALOX15HSD17B10
SCHEMBL14883479 0.76 HSD17B1 (0.45) MEN1KMT2AALDH1A1MAPTTDP1
SCHEMBL377438 0.75 CRHBP (0.43) MEN1KMT2AHTTALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623443-B1 METAL COMPLEX WITH FLUORINE SUBSTITUTION BEIJING SUMMER SPROUT TECH CO LTD (CN) 2022-05-18 EP disclosed
EP-1858890-B1 NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS BOEHRINGER INGELHEIM PHARMA (DE) 2010-04-14 EP disclosed
EP-0503958-B1 Heterocyclic compounds and their production NIPPON PAINT CO LTD (JP) 1998-09-23 EP disclosed