Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038732 | 0.77 | HSD17B10 (0.44) | ALDH1A1ALOX15CYP2A6NPC1POLB | |
| SCHEMBL6872360 | 0.74 | CA12 (0.37) | ALDH1A1NPSR1ALOX15HTTKMT2A | |
| SCHEMBL7978097 | 0.72 | ALDH1A1 (0.42) | ALDH1A1NPSR1ALOX15CYP2A6HTT | |
| SCHEMBL5516786 | 0.72 | ALDH1A1 (0.42) | ALDH1A1NPSR1ALOX15CYP2A6HTT | |
| SCHEMBL43388 | 0.72 | ALDH1A1 (0.42) | ALDH1A1NPSR1ALOX15CYP2A6HTT | |
| SCHEMBL29655310 | 0.70 | HTT (0.34) | ALDH1A1NPSR1ALOX15HTTKMT2A | |
| SCHEMBL9435737 | 0.69 | ALDH1A1 (0.38) | ALDH1A1NPSR1ALOX15CYP2A6HTT | |
| SCHEMBL8042435 | 0.69 | ALDH1A1 (0.34) | ALDH1A1NPSR1ALOX15CYP2A6HTT | |
| SCHEMBL10738575 | 0.69 | ALDH1A1 (0.42) | ALDH1A1NPSR1ALOX15HTTKMT2A | |
| SCHEMBL2455066 | 0.68 | ALDH1A1 (0.39) | ALDH1A1NPSR1ALOX15CYP2A6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802634-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | Compass Pharmaceuticals LLC (US) | 2007-07-04 | — | — | EP | claimed |
| WO-2006044826-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | COMPASS PHARMACEUTICALS LLC (US) | 2006-04-27 | — | — | WO | claimed |
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | claimed |
| EP-0054865-B1 | SUBSTITUTED 1-AZOLYL-BUTAN-2-ONES, THEIR PREPARATION AND THEIR APPLICATION AS FUNGICIDES AS WELL AS INTERMEDIATES | BAYER AG (DE) | 1986-02-26 | — | — | EP | claimed |
| US-4551464-A | AND SULFIMINO CARBOSTYRILS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-11-05 | — | — | US | claimed |
| EP-0083750-B1 | ANTIMYCOTIC AZOLYL BUTANOLS | BAYER AG (DE) | 1985-08-07 | — | — | EP | claimed |
| US-4442111-A | Antithrombotic sulfimino and sulfoximino indolinones-2 | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-04-10 | — | — | US | claimed |
| US-4116953-A | 2-PHENYL-3,1-BENZOXAZIN-4-ONES, PIGMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | claimed |
| US-4076819-A | ANTIINFLAMMATORY AGENTS, INHIBITOR OF BLOOD PLATELET AGGREGATION | PARCOR (FR) | 1978-02-28 | — | — | US | claimed |
| US-4042591-A | PIGMENTS, DISPERSE DYES | SANDOZ LTD. (CH) | 1977-08-16 | — | — | US | claimed |
| US-4006163-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | claimed |
| CN-106984291-B | Preparation and use of bis [ -6-oxo- (3-deoxycitric acid monoester-4) ] - β -cyclodextrin HPLC column material | 中南民族大学 | 2020-04-21 | — | — | CN | disclosed |
| CN-110179987-A | For treating the therapeutic agent of inflammatory lung disease | 加的夫大学学院咨询有限公司 | 2019-08-30 | — | — | CN | disclosed |
| EP-1749880-B1 | Cleaning compositions and methods | RECKITT BENCKISER UK LTD (GB) | 2013-04-17 | — | — | EP | disclosed |
| US-8258092-B2 | Cleaning compositions and methods | RECKITT BENCKISER (UK) LIMITED (GB) | 2012-09-04 | — | — | US | disclosed |
| US-4017468-A | IMIDE-MODIFIED TERPOLYMERSSULFUR-CURED RUBBER, TIRES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-4016151-A | Phenyl-substituted phthalazone azo dyes with a coupling component of the phenol, napthol, acetoacetarylide, pyrazolone, quinolone, pyridine, pyrimidone or isoquinolone series | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-4006163-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-3974163-A | VULCANIZATION INHIBITOR | MONSANTO COMPANY (US) | 1976-08-10 | — | — | US | disclosed |
| US-3935311-A | Substitute pyridinol-containing compositions and methods for the treatment of coccidiosis | SANKYO COMPANY LIMITED (JA) | 1976-01-27 | — | — | US | disclosed |