SCHEMBL29655393

SCHEMBL29655393

C=C[C@H]1[C@H](O[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(=O)c3cccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c3O)[C@H](OC(C)=O)[C@H]2OC(C)=O)OC=C2C(=O)OCC[C@]21O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.36
SLC28A3 Q9HAS3 2/20 0.35
P4HB P07237 1/20 0.34
PDIA4 P13667 1/20 0.34
PDIA3 P30101 1/20 0.34
LGALS9 O00182 1/20 0.33
LGALS1 P09382 1/20 0.33
LGALS3 P17931 1/20 0.33
LGALS7; LGALS7B P47929 1/20 0.33
ANTXR2 P58335 1/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29426019 0.98 SLC28A3 (0.36) STAT3SLC28A3P4HBPDIA4PDIA3
SCHEMBL29655328 0.83 STAT3 (0.58) STAT3SLC28A3P4HBPDIA4PDIA3
SCHEMBL29425981 0.81 STAT3 (0.56) STAT3SLC28A3P4HBPDIA4PDIA3
SCHEMBL29655361 0.81 STAT3 (0.54) STAT3P4HBPDIA4PDIA3LGALS9
Swertiamarin SCHEMBL422560 0.77 STAT3 (0.57) STAT3PTPN1
SCHEMBL29425739 0.73 STAT3 (0.69) STAT3SLC28A3LGALS9LGALS1LGALS3
SCHEMBL29655256 0.71 STAT3 (0.39) STAT3SLC28A3
SCHEMBL30914550 0.68 STAT3 (0.46) STAT3P4HBPDIA4PDIA3ANTXR2
SCHEMBL29974336 0.67 STAT3 (0.43) STAT3PTPN1
SCHEMBL11200785 0.67 CYP2D6 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119563642-A Corn seed coating agent and preparation method and application thereof 甘肃省农业工程技术研究院 2025-03-07 CN disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
CN-114315691-B Asymmetric squaraine colorimetric probe for identifying copper ions and application thereof 常州大学 2023-08-22 CN disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 STAT3 2027/4885SLC28A3 1319/4885P4HB 4001/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 STAT3 2027/4885SLC28A3 1319/4885P4HB 4001/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 STAT3 2027/4885SLC28A3 1319/4885P4HB 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.