Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.63 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | FES | P07332 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27844259 | 1.00 | KIF11 (0.63) | KIF11PLK4CHEK1AURKACHUK | |
| Dibenzofuran SCHEMBL28842309 | 0.89 | KIF11 (0.58) | KIF11PLK4CHEK1AURKACHUK | |
| Dibenzothiophene SCHEMBL28150020 | 0.89 | KIF11 (0.58) | KIF11PLK4CHEK1AURKACHUK | |
| SCHEMBL32668555 | 0.87 | KIF11 (0.63) | KIF11PLK4CHEK1AURKACHUK | |
| SCHEMBL725164 | 0.87 | KIF11 (0.63) | KIF11PLK4CHEK1AURKACHUK | |
| SCHEMBL26171230 | 0.84 | KIF11 (0.54) | KIF11CAMK2BCAMK2GCAMK2DMEN1 | |
| SCHEMBL10312976 | 0.81 | KIF11 (0.62) | KIF11MEN1MAPTKMT2ABCHE | |
| SCHEMBL21765733 | 0.78 | KIF11 (0.52) | KIF11BCHEACHEIMPDH2IMPDH1 | |
| SCHEMBL29539315 | 0.78 | KIF11 (0.81) | KIF11MAPTKCNH2SCN10A | |
| SCHEMBL2606005 | 0.78 | KIF11 (0.81) | KIF11MAPTKCNH2SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372261-B | Method for preparing 1-bromo/chloro carbazole and derivatives thereof | 中国科学院兰州化学物理研究所 | 2023-06-27 | — | — | CN | disclosed |
| CN-113620811-B | Halogenation method of aromatic compound | 中国科学院兰州化学物理研究所 | 2022-05-24 | — | — | CN | disclosed |