SCHEMBL21765733

SCHEMBL21765733

CC(C)(C)c1cccc2[nH]c3cccc(C(C)(C)C)c3c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.52
CA2 P00918 1/20 0.46
GABRA1 P14867 2/20 0.40
GABRB2 P47870 2/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
IMPDH2 P12268 1/20 0.38
IMPDH1 P20839 1/20 0.38
GPR3 P46089 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.34
TRPA1 O75762 1/20 0.34
ALOX12 P18054 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10312976 0.86 KIF11 (0.62) KIF11GABRA1GABRB2ALDH1A1IMPDH2
SCHEMBL28154006 0.80 KIF11 (0.47) KIF11CA2GABRA1GABRB2
SCHEMBL27844259 0.78 KIF11 (0.63) KIF11GABRA1GABRB2IMPDH2IMPDH1
SCHEMBL725164 0.78 KIF11 (0.63) KIF11GABRA1GABRB2IMPDH2IMPDH1
Benzene SCHEMBL28154005 0.78 KIF11 (0.46) KIF11CA2GABRA1GABRB2
SCHEMBL32668555 0.78 KIF11 (0.63) KIF11GABRA1GABRB2IMPDH2IMPDH1
SCHEMBL29655428 0.78 KIF11 (0.63) KIF11GABRA1GABRB2IMPDH2IMPDH1
SCHEMBL26171230 0.78 KIF11 (0.54) KIF11GABRA1GABRB2BCHEACHE
SCHEMBL22251522 0.78 GABRA1 (0.37) KIF11CA2GABRA1GABRB2TRPA1
Hydrochloric Acid SCHEMBL8463398 0.77 KIF11 (0.41) KIF11CA2GABRA1GABRB2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165021-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-25 US disclosed
WO-2020039708-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT 国立大学法人九州大学 2020-02-27 WO disclosed