Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 6/20 | 0.58 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.57 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | NPY4R | P50391 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | MC5R | P33032 | 1/20 | 0.53 |
| ▸ | MC3R | P41968 | 1/20 | 0.53 |
| ▸ | MC1R | Q01726 | 1/20 | 0.53 |
| ▸ | EED | O75530 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29656083 | 0.96 | C5AR1 (0.61) | CXCR4KISS1RC5AR1NPY1RNPY2R | |
| SCHEMBL31489038 | 0.88 | KISS1R (0.60) | CXCR4KISS1RC5AR1NPY1RNPY2R | |
| SCHEMBL29845337 | 0.87 | CXCR4 (0.58) | CXCR4KISS1RC5AR1NPY1RNPY2R | |
| SCHEMBL29913515 | 0.87 | CXCR4 (0.62) | CXCR4C5AR1NPY1RNPY2RNPY4R | |
| SCHEMBL31182720 | 0.87 | NPY2R (0.69) | CXCR4NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30381557 | 0.86 | KISS1R (0.59) | CXCR4KISS1RC5AR1NPY1RNPY2R | |
| SCHEMBL31488939 | 0.86 | KISS1R (0.63) | CXCR4KISS1RC5AR1NPY1RNPY2R | |
| SCHEMBL30176440 | 0.86 | NPY1R (0.64) | CXCR4C5AR1NPY1RNPY2RNPY4R | |
| SCHEMBL31606491 | 0.86 | C5AR1 (0.61) | CXCR4KISS1RC5AR1NPY1RNPY2R | |
| SCHEMBL30007711 | 0.86 | KISS1R (0.62) | CXCR4KISS1RC5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2022-05-31 | — | — | US | claimed |
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | CYP24A1, CYP27B1, CYP2R1 | CXCR4 1077/4885KISS1R 2684/4885C5AR1 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.