Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453068 | 0.95 | THRB (0.41) | THRBALOX5TDP1POLBAPEX1 | |
| SCHEMBL2252926 | 0.94 | ALOX5 (0.36) | THRBALOX5TDP1POLBAPEX1 | |
| Iodide SCHEMBL2252207 | 0.94 | THRB (0.40) | THRBALOX5TDP1POLBAPEX1 | |
| Bromide SCHEMBL2250528 | 0.94 | THRB (0.40) | THRBALOX5TDP1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL1191038 | 0.94 | THRB (0.40) | THRBALOX5TDP1POLBAPEX1 | |
| Sulfuric Acid SCHEMBL2793234 | 0.82 | THRB (0.45) | THRBALOX5TSHRTYRPPARG | |
| SCHEMBL11693537 | 0.80 | THRB (0.41) | THRBALOX5TDP1POLBAPEX1 | |
| SCHEMBL30530483 | 0.80 | THRB (0.41) | THRBALOX5TDP1POLBAPEX1 | |
| SCHEMBL9354401 | 0.79 | THRB (0.42) | THRBALOX5TDP1POLBAPEX1 | |
| SCHEMBL2256992 | 0.77 | ALOX5 (0.43) | THRBALOX5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120132843-A1 | USE OF COMPOSITE MATERIALS BASED ON CARBON NANOTUBES AS THICKENING AGENTS FOR AQUEOUS SOLUTIONS | C.N.R.S. (FR) | 2012-05-31 | — | — | US | claimed |
| US-7772340-B2 | Alkoxyamines originating from β-phoshorated nitroxides and use thereof in radical polymerisation | ARKEMA FRANCE (FR) | 2010-08-10 | — | — | US | claimed |
| US-7635740-B2 | Method for radical emulsion polymerisation using hydrosoluble alkoxyamines | ARKEMA FRANCE (FR) | 2009-12-22 | — | — | US | claimed |
| US-20070123669-A1 | Method for radical emulsion polymerisation using hydrosoluble alkoxyamines | ARKEMA FRANCE (FR) | 2007-05-31 | — | — | US | claimed |