SCHEMBL29657205

SCHEMBL29657205

COC1=CC(P(=O)(OC)OC)N(C)c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.35
GPR3 P46089 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TTR P02766 2/20 0.33
HSP90AA1 P07900 1/20 0.32
KDM4E B2RXH2 5/20 0.32
ALDH1A1 P00352 5/20 0.32
GAA P10253 1/20 0.32
LMNA P02545 2/20 0.32
CDC25A P30304 2/20 0.32
CDC25B P30305 2/20 0.32
PTPN1 P18031 1/20 0.32
IDO1 P14902 1/20 0.32
HPGD P15428 4/20 0.31
CASP1 P29466 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CES1 P23141 1/20 0.30
MAP2K7 O14733 1/20 0.30
GMNN O75496 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29657214 0.84 GPR3 (0.36) GPR84GPR3MEN1KMT2ATTR
SCHEMBL29657203 0.70 GPR3 (0.51) GPR3MEN1KMT2AKDM4EALDH1A1
SCHEMBL29657186 0.70 P2RX4 (0.38) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL20495487 0.65 GPR3 (0.38) GPR3MEN1KMT2ATTRKDM4E
SCHEMBL29657220 0.62 HDAC4 (0.44) GPR84GPR3GAALMNA
SCHEMBL23356621 0.58 HDAC4 (0.40) MEN1KMT2AHSP90AA1KDM4EALDH1A1
SCHEMBL18499222 0.58 PTPN1 (0.41) GPR84MEN1KMT2ATTRHSP90AA1
SCHEMBL7838080 0.58 GPR84 (0.61) GPR84MEN1KMT2ATTRHSP90AA1
SCHEMBL19854406 0.57 ALDH1A1 (0.49) GPR3MEN1KMT2ATTRKDM4E
SCHEMBL23356616 0.56 GPR3 (0.54) GPR3MEN1KMT2ATTRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286240-B2 Catalyst bound alpha radical and synthesis of OXO compounds using the same COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2022-03-29 US claimed
US-11286240-B2 Catalyst bound alpha radical and synthesis of OXO compounds using the same COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2022-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286240-B2 Catalyst bound alpha radical and synthesis of OXO compounds using the same CBR1, POR, CAT GPR84 2191/4885GPR3 4248/4885MEN1 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.